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Thalidomide ( /θəˈlɪdəmaɪd/) was introduced as a sedative drug in the late 1950s that was typically used to treat the symptoms of morning sickness.[2] It was sold in a number of countries across the world from 1957 until 1961, when it was withdrawn from the market after being found to be a cause of birth defects in what has been called "one of the biggest medical tragedies of modern times".[3]
There is now a growing clinical interest in thalidomide, and it has been found to be effective in combination with dexamethasone to treat multiple myeloma.[4] It is also used to treat erythema nodosum leprosum, a complication of leprosy, with strict controls on its use to prevent birth defects.[5] Research is ongoing in its use to treat other cancers and autoimmune conditions, although its use, including its testing in the developing world, remains controversial.[6][4][7] The thalidomide tragedy led to much stricter testing being required for drugs and pesticides before they can be licensed.[8]
Source: http://en.wikipedia.org/wiki/Thalidomide |
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【参加活动 -- 温柔 坚硬 随性 幽默， 爱这充满个性的墨尔本 (2015-2-16) 胡须康 
发表于 2012-1-23 14:20
