|
|
此文章由 henry_chen 原创或转贴，不代表本站立场和观点，版权归 oursteps.com.au 和作者 henry_chen 所有！转贴必须注明作者、出处和本声明，并保持内容完整
阿尔茨海默氏症（老年痴呆症）的治疗突破
悉尼大学的研究人员声称：阿尔茨海默氏症取得突破，将直接导致新的治疗。
他们的研究表明，两个关键蛋白质相互作用引起大脑退化的老年痴呆症称为阿尔茨海默氏症。
Gotz教授说，这是史无前例的步骤。
Gotz教授说: 研究表明 , 大脑中的神经细胞外的一种蛋白质构成不溶性团块与其他神经细胞内蛋白质发生相互作用，”
Gotz教授说，他的团队用这些知识来打断实验小鼠疾病的互动发展。
“我们基本上是能够避免早期阿尔茨海默氏症，”他说。
“所以，以小鼠做研究模型, (因为它已被改基因, 而且最终会发展成阿尔茨海默氏症)
当我们充分介入干预实验小鼠的阿尔茨海默氏症早期症状发展，那么我们可以避免老年痴呆症出现在这实验小鼠模型身上。”
“我们完全可以拯救所有的阿尔茨海默氏症所引起症状: 癫痫发作，延长寿命。”
他说，“可能仅仅需要5年时间, 这种新治疗技术就可以治疗人类”
====================================================
Alzheimer's breakthrough could lead to treatment
Researchers at the University of Sydney claim a breakthrough in research into Alzheimer's disease will lead directly to a new treatment.
Their study shows how two key proteins interact to trigger the brain degeneration known as Alzheimer's.
Professor Jurgen Gotz says it is ground-breaking.
"We show that a protein which forms insoluble clumps outside of the nerve cells in the brain interacts with another protein inside the nerve cells," he said.
Professor Gotz says his team then used that knowledge to interrupt the interaction in mice developing the disease.
"We are basically able to prevent, at an early stage, Alzheimer's disease," he said.
"So when we interfere early enough in the mouse model which would eventually develop Alzheimer's disease - because it has been genetically modified - then we can prevent Alzheimer's disease in this mouse model."
"We can completely rescue all Alzheimer's effects, the seizures, the reduced lifespan."
He says development of a treatment for humans might be just five years away.
http://www.abc.net.au/news/stori ... .htm?section=justin |
评分
-
查看全部评分
|
做板凳记 (2009-7-9) ranger 
发表于 2010-7-25 02:25
发表于 2010-7-27 22:35
