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吃葡萄柚一定要注意：
http://en.wikipedia.org/wiki/Grapefruit#Drug_interactions
Grapefruit can have a number of interactions with drugs,[20] often increasing the effective potency of compounds. Grapefruit contains a number of polyphenolic compounds, including the flavanone naringin, alongside the two furanocoumarins bergamottin and dihydroxybergamottin. These inhibit the drug-metabolizing enzyme isoform CYP3A4 predominately in the small intestine, but at higher doses also inhibit hepatic CYP3A4.[21] It is via inhibition of this enzyme that grapefruit increases the effects of a variety of drugs by increasing their bioavailability.[22][23][24][25][26][27] In particular grapefruit and bitter oranges are known to interact with statins. Because of this unique property, grapefruit has a very bitter taste when mixed with milk or similar dairy products.
Grapefruit juice may be the first drug-interacting fruit juice documented, but apple and orange juices have been also implicated in interfering with etoposide, a chemotherapy drug, some beta blocker drugs used to treat high blood pressure, and cyclosporine, taken by transplant patients to prevent rejection of their new organs.[28] Some citrus-based carbonated beverages (e.g., "Sun Drop") also contain enough grapefruit juice to cause drug interactions, particularly in patients taking cyclosporine.
Unlike other fruits, grapefruit contains a large amount of naringin, and it can take up to 72 hours before the effects of the naringin on the CYP3A4 enzyme are seen. This is particularly problematic due to the fact that only 4 oz of grapefruit contain enough naringin to inhibit the metabolism of substrates of CYP3A4.
http://zh.wikipedia.org/wiki/%E8%91%A1%E8%90%84%E6%9F%9A%E6%B1%81
葡萄柚汁是千万不能与药物一起服用的，因为葡萄柚汁中的部分类黄酮与香豆素（Coumarin）成分会抑制一种肠道中的代谢酵素，许多常用口服药物必须依赖这种酵素进行代谢，一旦酵素作用被抑制而使代谢无法进行，这些药物将会在体内累积而超过正常浓度，可能副作用及毒性。
已知会因葡萄柚汁而抑制正常代谢的药物成分包括：
某些称为“钙离子通道阻断剂”的心血管药物与葡萄柚汁并用时可能发生头痛、脸潮红，甚至严重低血压。[1]
用于免疫疾病与器官移植的药物Cyclosporin与葡萄柚汁并用时将提高药物在血中的浓度，使患者呕吐、头重脚轻、腹痛甚至引发肾毒性等症状。
某些用于治疗皮肤过敏或是流鼻水的抗组织胺药若并服葡萄柚汁，将造成体内药物堆积，延长心脏QT波，引起心室心律不整，严重时将致命。
当与葡萄柚汁并用时，茶碱、咖啡因、雌激素、皮质类固醇、奎尼丁等都会减少代谢。
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