barrett 食管

dudu2007

大家知不知道barrett 食管 这个病呀

澳洲有什么好的治疗方法吗，谢谢

Sharlene

Reflux occurs when the acidic contents of the stomach squeeze or ‘slosh’ back through the sphincter and enter the lower oesophagus, causing symptoms such as heartburn (a burning sensation in the lower chest) or regurgitation.

People who experience persistent symptoms of reflux (for more than five years) are at risk of developing Barrett’s oesophagus. This is a condition where the cells lining the lower oesophagus change in appearance to resemble those of the stomach and intestine. Importantly, Barrett’s oesophagus is a risk factor for cancer of the lower oesophagus. The chronic reflux of gastric juices causes these cellular changes, which may eventually turn cancerous.

Cancer risk
In a percentage of cases, these cellular changes turn cancerous. Studies in the United States have discovered that the rate of cancer caused by Barrett’s oesophagus is on the increase.

If detected early, cancer of the oesophagus can be treated successfully by surgery. However, many people with cancer caused by Barrett’s oesophagus don’t seek medical advice until the tumour is too advanced for curative treatment.

Diagnosis
Diagnosing Barrett’s oesophagus involves a number of tests, including:

-Endoscopic biopsy 胃镜活检

-Twenty-four hour ambulatory pH monitoring – a thin wire is threaded through the nose into the oesophagus and connected to a small recorder. This device is worn on the body, usually for 24 hours. This records the level of acid bathing the lower gullet and is an effective way of proving that therapy is adequate.

-Regular examinations
Once Barrett’s oesophagus has been diagnosed, regular examinations (every two to three years) are needed to check for dysplasia. Dysplasia is a further microscopic change in the cells that is recognisable in the biopsy and indicates a high risk of cancer. In this situation, endoscopies need to be performed more frequently (every six months).

Treatment

×Medications – once Barrett’s oesophagus has been diagnosed, it is essential that treatment is given to eliminate acid reflux.

×Endoscopic therapy – if severe dysplasia or carcinoma is found, this can sometimes be removed with microsurgery performed using an endoscope.

＊Surgery – an anti-reflux operation can be performed. This is usually only done if the medications are ineffective. If cancerous cells or severe dysplasia has been detected, the lower oesophagus will need to be surgically removed.

[ 本帖最后由 Sharlene 于 2009-4-20 21:19 编辑 ]