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zzn 发表于 2021-10-12 21:14 
请问自然免疫保护率相当AZ好多倍的说法,有可靠出处吗?
新闻是指这个
https://www.thegatewaypundit.com ... d-natural-immunity/
A new study out of Israel has seemingly confirmed that individuals who have natural immunity have better protection against the NEW DELTA VARIANT than people who are fully vaccinated.
The team of researchers, from Maccabi Healthcare and Tel Aviv University, published their study earlier this week to medRxiv.org.
‘This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, ‘ the team of researchers wrote.
Not just a little bit better either. People who have taken both doses of the Pfizer jab are 13 TIMES more likely to have a breakthrough infection, and are even at a “greater risk for Covid-19 hospitalizations.”
The researchers conducted an extensive study on 800,000 individuals that were broken into 3 groups. People who had received either one or two doses of the Pfizer-BioNTech COVID-19 vaccine were compared with unvaccinated individuals who have natural immunity, because they had already recovered from the virus.
SARS-CoV-2-naïve vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well.
When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
MOST NOTABLY, the study also found – Three months after a 2nd dose, the risk of contracting Covid was 13.06 times higher among the vaccinated and they are 27 TIMES more likely to experience symptoms.
After adjusting for comorbidities, we found a 27.02-fold risk (95% CI, 12.7 to 57.5) for symptomatic breakthrough infection as opposed to symptomatic reinfection (P<0.001) (Table 2b). None of the covariates were significant, except for age ≥60 years.
其中提到的论文是指这个
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1
题目:
Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
结果:
SARS-CoV-2-naïve vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold (95% CI, 4.85 to 7.33) increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
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