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本帖最后由 Hetbert 于 2021-7-17 01:18 编辑
shuobuzuji 发表于 2021-7-16 10:07 
两针打完的感染后传染率会降吗?
会的。
传染率差不多下降一半。因为抗体可以有效降低感染者的病毒载量。以色列测了5000个接种辉瑞疫苗后被突破感染的新冠感染者的鼻腔病毒载量,相对于未接种感染者,病毒载量显著降低。
In April, Public Health England reported the results of a large study of COVID-19 transmission involving more than 365,000 households with a mix of vaccinated and unvaccinated members.
It found immunisation with either the Pfizer or AstraZeneca vaccine reduced the chance of onward virus transmission by 40–60%. This means that if someone became infected after being vaccinated, they were only around half as likely to pass their infection on to others compared to infected people who were not vaccinated.
One study from Israel, which leads the world in coronavirus vaccinations, gives some clues about what is behind this reduced transmission. Researchers identified nearly 5000 cases of breakthrough infection in previously vaccinated people, and determined how much virus was present in their nose swabs. Compared to unvaccinated people, the amount of virus detected was significantly lower in those who got vaccinated.
More virus in the nose has been linked to greater infectiousness and increased risks of onward transmission.
These studies show vaccination is likely to substantially reduce virus transmission by reducing the pool of people who become infected, and reducing virus levels in the nose in people with breakthrough infections.
https://www1.racgp.org.au/newsgp ... d-vaccines-do-reduc
https://www.nature.com/articles/s41591-021-01316-7
不过,不同技术路线的疫苗最后效果不大一样。AZ疫苗激活的T细胞更多,被突破性感染后更不容易死;
辉瑞的疫苗激活的抗体更多,被突破性感染后更不容易传染,但死亡率稍稍高一点。根据美国CDC的不完全统计,被突破性感染后,死亡率是2%。
A total of 10,262 SARS-CoV-2 vaccine breakthrough infections had been reported from 46 U.S. states and territories as of April 30, 2021. Among these cases, 6,446 (63%) occurred in females, and the median patient age was 58 years (interquartile range = 40–74 years). Based on preliminary data, 2,725 (27%) vaccine breakthrough infections were asymptomatic, 995 (10%) patients were known to be hospitalized, and 160 (2%) patients died
https://www.cdc.gov/mmwr/volumes/70/wr/mm7021e3.htm |
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